AIP antibody (AA 91-330) (Fluoro594)

Catalog No. ABIN7970240

The Fluoro594-conjugated Mouse Monoclonal anti-AIP antibody (Clone 10G8) (ABIN7970240) specifically detects AIP in FACS. The antibody is reactive with Human, Rat, Mouse and Monkey samples.

Quick Overview for AIP antibody (AA 91-330) (Fluoro594) (ABIN7970240)

Target: AIP (Aryl Hydrocarbon Receptor Interacting Protein (AIP))

Reactivity: Human, Rat, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This AIP antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Clone: 10G8

Product Details anti-AIP Antibody (Fluoro594)

Binding Specificity: AA 91-330

Purpose: Anti-ARA9/AIP Antibody (monoclonal, 10G8) Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human ARA9 shares 95% amino acid (aa) sequence identity with both mouse,rat ARA9.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ARA9 recombinant protein (Position: D91-H330). Human ARA9 shares 95% amino acid (aa) sequence identity with both mouse and rat ARA9.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for AIP

Target: AIP (Aryl Hydrocarbon Receptor Interacting Protein (AIP))

Alternative Name: AIP

Background:

Background: AIP, also known as, ARA9 or XAP-2, is a protein that in humans is encoded by the AIP gene. This gene is mapped to 11q13.2. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. AIP may play a positive role in aryl hydrocarbon receptor-mediated signalling possibly by influencing its receptivity for ligand and/or its nuclear targeting. It has been shown that AIP is the cellular negative regulator of the hepatitis B virus (HBV) X protein. AIP mutations may be the cause of a familial form of acromegaly, familial isolated pituitary adenoma (FIPA).

Gene Full Name: AHR interacting HSP90 co-chaperone

Gene ID: 9049

UniProt: O00170