NMDAR2A antibody (AA 851-950)

Catalog No. ABIN747353

Product Details anti-NMDAR2A Antibody

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Binding Specificity: AA 851-950

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMDAR2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NMDAR2A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-NMDAR2A antibody (ABIN747353)

Ku, Li, Gao, Zhang, Yan, Ji, Li, Sang: "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration." in: Particle and fibre toxicology, Vol. 14, Issue 1, pp. 34, (2018) (PubMed).

Ji, Zhuang, Ji, Wu, Gu, Gao, Pan, Hu: "TFP5 peptide, derived from CDK5-activating cofactor p35, provides neuroprotection in early-stage of adult ischemic stroke." in: Scientific reports, Vol. 7, pp. 40013, (2017) (PubMed).

Zhao, Li, Wei, Savage, Zhou, Ma: "Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring." in: Neurobiology of disease, Vol. 68, pp. 145-55, (2014) (PubMed).

Target Details for NMDAR2A

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Alternative Name: NMDAR2A (GRIN2A Products)

Background:

Synonyms: LKS, EPND, FESD, NR2A, GluN2A, NMDAR2A, Glutamate receptor ionotropic, NMDA 2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, hNR2A, GRIN2A

Background: NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.

Gene ID: 2903

UniProt: Q12879

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity