Arylsulfatase A antibody (C-Term) (Cy3)

Catalog No. ABIN7970336

The Cy3-conjugated Mouse Monoclonal anti-Arylsulfatase A antibody (Clone 4C10) (ABIN7970336) specifically detects Arylsulfatase A in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Arylsulfatase A antibody (C-Term) (Cy3) (ABIN7970336)

Target: Arylsulfatase A (ARSA)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Arylsulfatase A antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Clone: 4C10

Product Details anti-Arylsulfatase A Antibody (Cy3)

Binding Specificity: C-Term

Purpose: Anti-ARSA Antibody (monoclonal, 4C10) Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by six amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ARSA, different from the related mouse sequence by six amino acids.

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Arylsulfatase A

Target: Arylsulfatase A (ARSA)

Alternative Name: ARSA

Background:

Background: Arylsulfatase A (ARSA) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate intocerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. ARSA is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

Gene Full Name: arylsulfatase A

Gene ID: 410

UniProt: P15289