BOK antibody (AA 1-177) (Cy3)

Catalog No. ABIN7972487

The Cy3-conjugated Rabbit Polyclonal anti-BOK antibody (ABIN7972487) specifically detects BOK in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BOK antibody (AA 1-177) (Cy3) (ABIN7972487)

Target: BOK (BCL2-Related Ovarian Killer (BOK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BOK antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-BOK Antibody (Cy3)

Binding Specificity: AA 1-177

Purpose: Anti-BOK Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human BOK recombinant protein (Position: M1-C177).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for BOK

Target: BOK (BCL2-Related Ovarian Killer (BOK))

Alternative Name: BOK

Background:

Background: The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.

Gene Full Name: BCL2 family apoptosis regulator BOK

Gene ID: 666

UniProt: Q9UMX3

Pathways: Positive Regulation of Endopeptidase Activity