Betacellulin antibody (AA 32-111) (APC)

Catalog No. ABIN7972670

The APC-conjugated Rabbit Polyclonal anti-Betacellulin antibody (ABIN7972670) specifically detects Betacellulin in FACS. The antibody is reactive with Human samples.

Quick Overview for Betacellulin antibody (AA 32-111) (APC) (ABIN7972670)

Target: Betacellulin (BTC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Betacellulin antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Betacellulin Antibody (APC)

Binding Specificity: AA 32-111

Purpose: Anti-BTC Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human BTC recombinant protein (Position: D32-Y111).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Betacellulin

Target: Betacellulin (BTC)

Alternative Name: BTC

Background:

Background: Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.

Gene Full Name: betacellulin

Gene ID: 685

UniProt: P35070

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway