Betacellulin antibody (AA 32-111) (Fluoro647)

Catalog No. ABIN7972683

This Rabbit Polyclonal antibody specifically detects Betacellulin in FACS. It exhibits reactivity toward Mouse.

Quick Overview for Betacellulin antibody (AA 32-111) (Fluoro647) (ABIN7972683)

Target: Betacellulin (BTC)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Betacellulin antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Betacellulin Antibody (Fluoro647)

Binding Specificity: AA 32-111

Purpose: Anti-Btc Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Btc recombinant protein (Position: D32-Y111).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Betacellulin

Target: Betacellulin (BTC)

Alternative Name: Btc

Background:

Background: Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.

Gene Full Name: betacellulin, epidermal growth factor family member

Gene ID: 12223

UniProt: Q05928

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway