Betacellulin antibody (AA 32-111)

Catalog No. ABIN7972684

The Rabbit Polyclonal anti-Betacellulin antibody is suitable to detect Betacellulin in samples from Mouse. It has been validated for WB, IHC and ELISA.

Quick Overview for Betacellulin antibody (AA 32-111) (ABIN7972684)

Target: Betacellulin (BTC)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Betacellulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Grade: Carrier-free

Product Details anti-Betacellulin Antibody

Binding Specificity: AA 32-111

Purpose: Anti-Btc Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Btc Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Btc recombinant protein (Position: D32-Y111).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.5-1 μg/mL, Mouse Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Betacellulin

Target: Betacellulin (BTC)

Alternative Name: Btc

Background:

Background: Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.

Gene Full Name: betacellulin, epidermal growth factor family member

Molecular Weight: 26 kDa

Gene ID: 12223

UniProt: Q05928

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway