BID antibody (AA 1-195) (Fluoro647)

Catalog No. ABIN7972716

This Rabbit Polyclonal antibody specifically detects BID in FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for BID antibody (AA 1-195) (Fluoro647) (ABIN7972716)

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BID antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-BID Antibody (Fluoro647)

Binding Specificity: AA 1-195

Purpose: Anti-Bid Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Mouse Bid shares 64.6%,87.2% amino acid (aa) sequence identity with human,rat Bid,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Bid recombinant protein (Position: M1-D195). Mouse Bid shares 64.6% and 87.2% amino acid (aa) sequence identity with human and rat Bid, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for BID

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Alternative Name: Bid

Background:

Background: BID (BH3-Interacting Domain Death Agonist), is a pro-apoptotic member of the Bcl-2 protein family. The BCL2 family of proteins consists of both antagonists and agonists that regulate apoptosis and compete through dimerization. By fluorescence in situ hybridization, the human BID gene is mapped to 22q11. It is reported the purification of a cytosolic protein that induces cytochrome c release from mitochondria in response to caspase-8, the apical caspase activated by cell surface death receptors such as FAS and TNF.

Gene Full Name: BH3 interacting domain death agonist

Gene ID: 12122

UniProt: P70444

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity