BMP5 antibody (C-Term) (Fluoro647)

Catalog No. ABIN7972892

The Fluoro647-conjugated Rabbit Polyclonal anti-BMP5 antibody (ABIN7972892) specifically detects BMP5 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BMP5 antibody (C-Term) (Fluoro647) (ABIN7972892)

Target: BMP5 (Bone Morphogenetic Protein 5 (BMP5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP5 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-BMP5 Antibody (Fluoro647)

Binding Specificity: C-Term

Purpose: Anti-BMP5 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by three amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human BMP-5, different from the related mouse sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for BMP5

Target: BMP5 (Bone Morphogenetic Protein 5 (BMP5))

Alternative Name: BMP5

Background:

Background: Bone morphogenetic protein 5?is a?protein?that in humans is encoded by the?BMP5?gene. This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. And this protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.

Gene Full Name: bone morphogenetic protein 5

Gene ID: 653

UniProt: P22003

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process