Cadherin 13 antibody (AA 149-692) (Fluoro550)

Catalog No. ABIN7973832

This Rabbit Polyclonal antibody specifically detects Cadherin 13 in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for Cadherin 13 antibody (AA 149-692) (Fluoro550) (ABIN7973832)

Target: Cadherin 13 (CDH13)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 13 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-Cadherin 13 Antibody (Fluoro550)

Binding Specificity: AA 149-692

Purpose: Anti-H Cadherin/CDH13 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human H Cadherin/CDH13 recombinant protein (Position: E149-A692).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Cadherin 13

Target: Cadherin 13 (CDH13)

Alternative Name: CDH13

Background:

Background: T-cadherin also known as cadherin 13, H-cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: cadherin 13

Gene ID: 1012

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization