Calpain 2 antibody (AA 500-700) (APC)

Catalog No. ABIN7974354

This Mouse Monoclonal antibody specifically detects Calpain 2 in FACS. It exhibits reactivity toward Human, Mouse and Monkey.

Quick Overview for Calpain 2 antibody (AA 500-700) (APC) (ABIN7974354)

Target: Calpain 2 (CAPN2)

Reactivity: Human, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calpain 2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: 8I6

Product Details anti-Calpain 2 Antibody (APC)

Binding Specificity: AA 500-700

Purpose: Anti-Calpain 2 CAPN2 Antibody (monoclonal, 8I6) APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human Calpain 2 recombinant protein (Position: R500-L700). Human Calpain 2 shares 93.5%,92.5% amino acid (aa) sequence identity with mouse,rat Calpain 2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Calpain 2 recombinant protein (Position: R500-L700). Human Calpain 2 shares 93.5% and 92.5% amino acid (aa) sequence identity with mouse and rat Calpain 2, respectively.

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Calpain 2

Target: Calpain 2 (CAPN2)

Alternative Name: CAPN2

Background:

Background: Calpain-2 catalytic subunit is a protein that in humans is encoded by the CAPN2 gene. The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported.

Gene Full Name: calpain 2

Gene ID: 824

UniProt: P17655