CES1 antibody (AA 99-206) (Fluoro647)

Catalog No. ABIN7974785

The Fluoro647-conjugated Mouse Monoclonal anti-CES1 antibody (Clone 3F10) (ABIN7974785) specifically detects CES1 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CES1 antibody (AA 99-206) (Fluoro647) (ABIN7974785)

Target: CES1 (Carboxylesterase 1 (CES1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CES1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Clone: 3F10

Product Details anti-CES1 Antibody (Fluoro647)

Binding Specificity: AA 99-206

Purpose: Anti-Liver Carboxylesterase 1/CES1 Antibody (monoclonal, 3F10) Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Liver Carboxylesterase 1/CES1 recombinant protein (Position: E99-A206).

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Alternative Name: CES1

Background:

Background: Liver carboxylesterase 1 also known as carboxylesterase 1 (CES1, hCE-1 or CES1A1) is an enzyme that in humans is encoded by the CES1 gene. This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Gene Full Name: carboxylesterase 1

Gene ID: 1066

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process