Caveolin 3 antibody (AA 1-55) (Fluoro488)

Catalog No. ABIN7976055

This Rabbit Polyclonal antibody specifically detects Caveolin 3 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Caveolin 3 antibody (AA 1-55) (Fluoro488) (ABIN7976055)

Target: Caveolin 3 (CAV3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 3 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Caveolin 3 Antibody (Fluoro488)

Binding Specificity: AA 1-55

Purpose: Anti-Caveolin-3/CAV3 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Caveolin-3/CAV3 recombinant protein (Position: M1-D55).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Caveolin 3

Target: Caveolin 3 (CAV3)

Alternative Name: CAV3

Background:

Background: Caveolin-3 is a protein that in humans is encoded by the CAV3 gene. This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Gene Full Name: caveolin 3

Gene ID: 859

UniProt: P56539

Pathways: Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity