CD70 antibody (AA 36-191) (Fluoro594)

Catalog No. ABIN7977344

The Fluoro594-conjugated Rabbit Polyclonal anti-CD70 antibody (ABIN7977344) specifically detects CD70 in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for CD70 antibody (AA 36-191) (Fluoro594) (ABIN7977344)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD70 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-CD70 Antibody (Fluoro594)

Binding Specificity: AA 36-191

Purpose: Anti-Cd70 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Cd70 recombinant protein (Position: C36-Q191).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: Cd70

Background:

Background: CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Gene Full Name: CD70 antigen

Gene ID: 21948

UniProt: O55237

Pathways: Cancer Immune Checkpoints