CD79b antibody (AA 29-229) (Cy3)

Catalog No. ABIN7977374

The Cy3-conjugated Rabbit Polyclonal anti-CD79b antibody (ABIN7977374) specifically detects CD79b in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CD79b antibody (AA 29-229) (Cy3) (ABIN7977374)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD79b antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-CD79b Antibody (Cy3)

Binding Specificity: AA 29-229

Purpose: Anti-CD79b Antibody Cy3 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human CD79b shares 70% amino acid (aa) sequence identity with mouse CD79b.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CD79b recombinant protein (Position: A29-E229). Human CD79b shares 70% amino acid (aa) sequence identity with mouse CD79b.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79B

Background:

Background: CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene. By fluorescence in situ hybridization, It is mapped to 17q23.3. The CD79B protein together with the related CD79A protein, forms a dimer associated with membrane bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR) which is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). CD79b also can enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

Gene Full Name: CD79b molecule

Sequence Similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene ID: 974

UniProt: P40259

Pathways: BCR Signaling