CD82 antibody (AA 32-266) (PE)

Catalog No. ABIN7977480

This Rabbit Polyclonal antibody specifically detects CD82 in FACS. It exhibits reactivity toward Mouse and Rat.

Quick Overview for CD82 antibody (AA 32-266) (PE) (ABIN7977480)

Target: CD82

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD82 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CD82 Antibody (PE)

Binding Specificity: AA 32-266

Purpose: Anti-CD82 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse CD82 recombinant protein (Position: V32-Y266).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CD82

Target: CD82

Alternative Name: Cd82

Background:

Background: CD82 (Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.

Gene Full Name: CD82 antigen

Gene ID: 12521

UniProt: P40237

Pathways: p53 Signaling