CDCA8 antibody (AA 72-280) (HRP)

Catalog No. ABIN7977985

The Rabbit Polyclonal anti-CDCA8 antibody is suitable to detect CDCA8 in samples from Human. It has been validated for WB, ELISA and IHC.

Quick Overview for CDCA8 antibody (AA 72-280) (HRP) (ABIN7977985)

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA8 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CDCA8 Antibody (HRP)

Binding Specificity: AA 72-280

Purpose: Anti-CDCA8 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human CDCA8 shares 76%,77.8% amino acid (aa) sequence identity with mouse,rat CDCA8,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CDCA8 recombinant protein (Position: D72-K280). Human CDCA8 shares 76% and 77.8% amino acid (aa) sequence identity with mouse and rat CDCA8, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDCA8

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Alternative Name: CDCA8

Background:

Background: Borealin is a protein that in humans is encoded by the CDCA8 gene. This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.

Gene Full Name: cell division cycle associated 8

Gene ID: 55143

UniProt: Q53HL2

Pathways: Cell Division Cycle, M Phase