Galectin 10 antibody (AA 2-142) (Biotin)

Catalog No. ABIN7978320

This Rabbit Polyclonal antibody specifically detects Galectin 10 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Galectin 10 antibody (AA 2-142) (Biotin) (ABIN7978320)

Target: Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galectin 10 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Galectin 10 Antibody (Biotin)

Binding Specificity: AA 2-142

Purpose: Anti-Galectin 10/CLC Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Galectin 10 recombinant protein (Position: S2-R142).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Galectin 10

Target: Galectin 10 (CLC) (Charcot-Leyden Crystal Protein (CLC))

Alternative Name: CLC

Background:

Background: Eosinophil lysophospholipase is an enzyme that in humans is encoded by the CLC gene. Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

Gene Full Name: Charcot-Leyden crystal galectin

Gene ID: 1178

UniProt: Q05315

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response