XCR1 antibody (AA 246-274) (APC)

Catalog No. ABIN7978416

This Rabbit Polyclonal antibody specifically detects XCR1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for XCR1 antibody (AA 246-274) (APC) (ABIN7978416)

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XCR1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-XCR1 Antibody (APC)

Binding Specificity: AA 246-274

Purpose: Anti-CCXCR1/XCR1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CCXCR1/XCR1 recombinant protein (Position: F246-N274).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for XCR1

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Alternative Name: XCR1

Background:

Background: The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Full Name: X-C motif chemokine receptor 1

Gene ID: 2829

UniProt: P46094