CCL3 antibody (AA 24-92) (Fluoro647)

Catalog No. ABIN7978693

The Rabbit Polyclonal anti-CCL3 antibody is suitable to detect CCL3 in samples from Rat. It has been validated for FACS.

Quick Overview for CCL3 antibody (AA 24-92) (Fluoro647) (ABIN7978693)

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL3 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-CCL3 Antibody (Fluoro647)

Binding Specificity: AA 24-92

Purpose: Anti-CCL3/Macrophage Inflammatory Protein 1 alpha Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Rat CCL3 shares 74%,91% amino acid (aa) sequences identity with human,mouse CCL3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived rat CCL3 recombinant protein (Position: A24-A92). Rat CCL3 shares 74% and 91% amino acid (aa) sequences identity with human and mouse CCL3, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CCL3

Target: CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

Alternative Name: CCL3

Background:

Background: Macrophage inflammatory protein-1 alpha (MIP-1 alpha), also called CCL3, LD78. The cDNA for CCL3 predicts a mature peptide of 69 amino acids with a molecular mass of 7,889 daltons. CCL3 is a member of a newly identified superfamily of small inducible proteins involved in inflammatory responses, wound healing and tumorigenesis. CCL3 is a chemokine that has pro-inflammatory and stem cell inhibitory activities in vitro. It constitutes an important second signal for mast cell degranulation in the conjunctiva in vivo and consequently for acute-phase disease.

Gene Full Name: C-C motif chemokine ligand 3

Sequence Similarities: Belongs to the pentaxin family.

Gene ID: 25542

UniProt: P50229

Pathways: Cellular Response to Molecule of Bacterial Origin, Autophagy