CCL6 antibody (AA 22-116) (Fluoro488)

Catalog No. ABIN7978741

The Rabbit Polyclonal anti-CCL6 antibody is suitable to detect CCL6 in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for CCL6 antibody (AA 22-116) (Fluoro488) (ABIN7978741)

Target: CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL6 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-CCL6 Antibody (Fluoro488)

Binding Specificity: AA 22-116

Purpose: Anti-CCL6 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse CCL6 recombinant protein (Position: G22-A116).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CCL6

Target: CCL6 (Chemokine (C-C Motif) Ligand 6 (CCL6))

Alternative Name: Ccl6

Background:

Background: Chemokine (C-C motif) ligand 6 (CCL6) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3, and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of CCL6 is greatly reduced.CCL6 can also be induced in the mouse lung by the cytokine interleukin 13. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.

Gene Full Name: C-C motif chemokine ligand 6

Gene ID: 20305

UniProt: P27784

Pathways: Response to Water Deprivation, Cell-Cell Junction Organization