CCL7 antibody (AA 24-97) (APC)

Catalog No. ABIN7978768

The Rabbit Polyclonal anti-CCL7 antibody is suitable to detect CCL7 in samples from Mouse. It has been validated for FACS.

Quick Overview for CCL7 antibody (AA 24-97) (APC) (ABIN7978768)

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL7 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-CCL7 Antibody (APC)

Binding Specificity: AA 24-97

Purpose: Anti-MCP3/CCL7 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse MCP3 shares 60%,95% amino acid (aa) sequences identity with human,rat MCP3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse MCP3 recombinant protein (Position: Q24-P97). Mouse MCP3 shares 60% and 95% amino acid (aa) sequences identity with human and rat MCP3, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Alternative Name: CCL7

Background:

Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

Gene Full Name: C-C motif chemokine ligand 7

Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

Gene ID: 20306

UniProt: Q03366