CHD2 antibody (AA 1124-1351) (Fluoro594)

Catalog No. ABIN7979854

The Rabbit Polyclonal anti-CHD2 antibody is suitable to detect CHD2 in samples from Human, Monkey, Mouse and Rat. It has been validated for FACS.

Quick Overview for CHD2 antibody (AA 1124-1351) (Fluoro594) (ABIN7979854)

Target: CHD2 (Chromodomain Helicase DNA Binding Protein 2 (CHD2))

Reactivity: Human, Monkey, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD2 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-CHD2 Antibody (Fluoro594)

Binding Specificity: AA 1124-1351

Purpose: Anti-CHD2 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human CHD2 recombinant protein (Position: R1124-K1351). Human CHD2 shares 97.4% amino acid (aa) sequence identity with mouse CHD2.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human CHD2 recombinant protein (Position: R1124-K1351). Human CHD2 shares 97.4% amino acid (aa) sequence identity with mouse CHD2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CHD2

Target: CHD2 (Chromodomain Helicase DNA Binding Protein 2 (CHD2))

Alternative Name: CHD2

Background:

Background: Chromodomain-helicase-DNA-binding protein 2 is an enzyme that in humans is encoded by the CHD2 gene. The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. CHD2 catalyzes the assembly of chromatin into periodic arrays, and the N-terminal region of CHD2, which contains tandem chromodomains, serves an auto-inhibitory role in both the DNA-binding and ATPase activities of CHD2.

Gene Full Name: chromodomain helicase DNA binding protein 2

Gene ID: 1106

UniProt: O14647