CHD8 antibody (AA 10-428) (Fluoro488)

Catalog No. ABIN7979885

The Fluoro488-conjugated Rabbit Polyclonal anti-CHD8 antibody (ABIN7979885) specifically detects CHD8 in FACS. The antibody is reactive with Human samples.

Quick Overview for CHD8 antibody (AA 10-428) (Fluoro488) (ABIN7979885)

Target: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD8 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-CHD8 Antibody (Fluoro488)

Binding Specificity: AA 10-428

Purpose: Anti-CHD8 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CHD8 recombinant protein (Position: D10-A428).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CHD8

Target: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Alternative Name: CHD8

Background:

Background: Chromodomain-helicase-DNA-binding protein 8 is an enzyme that in humans is encoded by the CHD8 gene. This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants.

Gene Full Name: chromodomain helicase DNA binding protein 8

Gene ID: 57680

UniProt: Q9HCK8

Pathways: Chromatin Binding