CHD8 antibody (AA 10-428)

Catalog No. ABIN7979893

The Rabbit Polyclonal anti-CHD8 antibody is suitable to detect CHD8 in samples from Human. It has been validated for WB, IHC, FACS and ELISA.

Quick Overview for CHD8 antibody (AA 10-428) (ABIN7979893)

Target: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Grade: Carrier-free

Product Details anti-CHD8 Antibody

Binding Specificity: AA 10-428

Purpose: Anti-CHD8 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-CHD8 Antibody. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CHD8 recombinant protein (Position: D10-A428).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHD8

Target: CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))

Alternative Name: CHD8

Background:

Background: Chromodomain-helicase-DNA-binding protein 8 is an enzyme that in humans is encoded by the CHD8 gene. This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahma and kismet domains, which are common to the subfamily of chromodomain-helicase-DNA binding proteins to which this protein belongs. This gene has been shown to function in several processes that include transcriptional regulation, epigenetic remodeling, promotion of cell proliferation, and regulation of RNA synthesis. Allelic variants of this gene are associated with autism spectrum disorder. Alternative splicing results in multiple transcript variants.

Gene Full Name: chromodomain helicase DNA binding protein 8

Molecular Weight: 300 kDa

Gene ID: 57680

UniProt: Q9HCK8

Pathways: Chromatin Binding