Nesprin3 antibody (AA 322-495) (PE)

Catalog No. ABIN7980034

The Rabbit Polyclonal anti-Nesprin3 antibody is suitable to detect Nesprin3 in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for Nesprin3 antibody (AA 322-495) (PE) (ABIN7980034)

Target: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nesprin3 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Nesprin3 Antibody (PE)

Binding Specificity: AA 322-495

Purpose: Anti-Nesprin3/SYNE3 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Nesprin3/SYNE3 recombinant protein (Position: R322-L495).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Nesprin3

Target: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Alternative Name: SYNE3

Background:

Background: Enables actin filament binding activity and cytoskeleton-nuclear membrane anchor activity. Involved in cytoskeleton organization, establishment of protein localization to membrane, and regulation of cell shape. Located in nuclear membrane. Part of meiotic nuclear membrane microtubule tethering complex. Biomarker of Huntington's disease.

Gene Full Name: spectrin repeat containing nuclear envelope family member 3

Gene ID: 161176

UniProt: Q6ZMZ3

Pathways: Maintenance of Protein Location