Nesprin3 antibody (AA 322-495)

Catalog No. ABIN7980036

This Rabbit Polyclonal antibody specifically detects Nesprin3 in WB, ELISA, IHC and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for Nesprin3 antibody (AA 322-495) (ABIN7980036)

Target: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nesprin3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-Nesprin3 Antibody

Binding Specificity: AA 322-495

Purpose: Anti-Nesprin3/SYNE3 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Nesprin3/SYNE3 Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Nesprin3/SYNE3 recombinant protein (Position: R322-L495).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Nesprin3

Target: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Alternative Name: SYNE3

Background:

Background: Enables actin filament binding activity and cytoskeleton-nuclear membrane anchor activity. Involved in cytoskeleton organization, establishment of protein localization to membrane, and regulation of cell shape. Located in nuclear membrane. Part of meiotic nuclear membrane microtubule tethering complex. Biomarker of Huntington's disease.

Gene Full Name: spectrin repeat containing nuclear envelope family member 3

Molecular Weight: 100 kDa

Gene ID: 161176

UniProt: Q6ZMZ3

Pathways: Maintenance of Protein Location