CIT antibody (AA 470-1505) (Biotin)

Catalog No. ABIN7980280

The Rabbit Polyclonal anti-CIT antibody is suitable to detect CIT in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and WB.

Quick Overview for CIT antibody (AA 470-1505) (Biotin) (ABIN7980280)

Target: CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIT antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-CIT Antibody (Biotin)

Binding Specificity: AA 470-1505

Purpose: Anti-CIT Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human CIT shares 95.2%,94.7% amino acid (aa) sequence identity with mouse,rat CIT,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CIT recombinant protein (Position: Q470-H1505). Human CIT shares 95.2% and 94.7% amino acid (aa) sequence identity with mouse and rat CIT, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CIT

Target: CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))

Alternative Name: CIT

Background:

Background: This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants.

Gene Full Name: citron rho-interacting serine/threonine kinase

Gene ID: 11113

UniProt: O14578

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection