CIT antibody (AA 470-1505)

Catalog No. ABIN7980290

The Rabbit Polyclonal anti-CIT antibody (ABIN7980290) specifically detects CIT in ELISA, WB and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CIT antibody (AA 470-1505) (ABIN7980290)

Target: CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIT antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-CIT Antibody

Binding Specificity: AA 470-1505

Purpose: Anti-CIT Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human CIT shares 95.2%,94.7% amino acid (aa) sequence identity with mouse,rat CIT,respectively.

Characteristics: Anti-CIT Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CIT recombinant protein (Position: Q470-H1505). Human CIT shares 95.2% and 94.7% amino acid (aa) sequence identity with mouse and rat CIT, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CIT

Target: CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))

Alternative Name: CIT

Background:

Background: This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants.

Gene Full Name: citron rho-interacting serine/threonine kinase

Molecular Weight: 231 kDa

Gene ID: 11113

UniProt: O14578

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection