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Integrin Alpha2b antibody (AA 351-450) (Cy7)

CD41 Reactivity: Human, Rat FACS, WB, IF (p), IF (cc) Host: Rabbit Polyclonal Cy7

Catalog No. ABIN748364

Datasheet as PDF

Target See all Integrin Alpha2b (CD41) Antibodies

Integrin Alpha2b (CD41)
Binding Specificity
15

5

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 351-450
Reactivity
143

31

20

7

6

5

3

3

2

2

2

1

1

1

1

1
Human, Rat
Host
96

48

22

1
Rabbit
Compatible Secondaries
Clonality
117

44

1
Polyclonal
Conjugate
65

17

13

12

6

4

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Integrin Alpha2b antibody is conjugated to Cy7
Application
121

44

30

22

22

21

12

12

10

9

5

4

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity

Human, Rat

Predicted Reactivity

Mouse,Cow,Horse,Rabbit

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b

Isotype

IgG

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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 Reactivity: Human FACS, WB, ELISA, IHC Host: Mouse Monoclonal unconjugated

anti-Integrin Alpha2b (CD41) (AA 351-450) antibody
CD41 Reactivity: Human, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p), Func Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Mouse FACS, ELISA, IHC (fro), IP, IHC (p) Host: Rat Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP2 unconjugated

anti-Integrin Alpha2b (CD41) antibody (Biotin)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 Biotin

anti-Integrin Alpha2b (CD41) antibody (FITC)
CD41 Reactivity: Human FACS Host: Mouse Monoclonal MEM-06 FITC

anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibody
CD41 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reactivity: Human, Non-Human Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated

Application Notes

FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date

12 months
Target

Integrin Alpha2b (CD41)

Alternative Name

Integrin alpha 2b/CD41 (CD41 Products)

Background

Synonyms: CD41, CD41B, GpIIb, AI172977, alphaIIb, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, Itga2b
Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Gene ID

16399

UniProt

Q9QUM0

Pathways

Integrin Complex