Claudin 2 antibody (AA 63-230) (APC)

Catalog No. ABIN7980430

The Rabbit Polyclonal anti-Claudin 2 antibody is suitable to detect Claudin 2 in samples from Human. It has been validated for FACS.

Quick Overview for Claudin 2 antibody (AA 63-230) (APC) (ABIN7980430)

Target: Claudin 2 (CLDN2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Claudin 2 Antibody (APC)

Binding Specificity: AA 63-230

Purpose: Anti-Claudin 2/CLDN2 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CLDN2 recombinant protein (Position: Q63-V230).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Claudin 2

Target: Claudin 2 (CLDN2)

Alternative Name: CLDN2

Background:

Background: Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.

Gene Full Name: claudin 2

Gene ID: 9075

UniProt: P57739

Pathways: Hepatitis C