PTGES2 antibody (AA 281-384)

Catalog No. ABIN748403

There are 4+ publications for this product available. The Rabbit Polyclonal anti-PTGES2 antibody is suitable to detect PTGES2 in samples from Mouse. It has been validated for FACS, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for PTGES2 antibody (AA 281-384) (ABIN748403)

Target: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGES2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PTGES2 Antibody

Binding Specificity: AA 281-384

Purpose: PTGES2 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse PGES2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PTGES2 antibody (ABIN748403)

Manaserh, Chikkamenahalli, Ravi, Dube, Park, Hill: "Ablating astrocyte insulin receptors leads to delayed puberty and hypogonadism in mice." in: PLoS biology, Vol. 17, Issue 3, pp. e3000189, (2019) (PubMed).

Chia, Liu, Feng, Tseng, Hung, Chen, Tan: "The Antinociceptive Effect of Light-Emitting Diode Irradiation on Incised Wounds Is Correlated with Changes in Cyclooxygenase 2 Activity, Prostaglandin E2, and Proinflammatory Cytokines." in: Pain research & management, Vol. 2017, pp. 4792489, (2017) (PubMed).

Liu, Li, Liu, She, Shi, Li, Wang, Jiang: "Activated hepatic stellate cells directly induce pathogenic Th17 cells in chronic hepatitis B virus infection." in: Experimental cell research, Vol. 359, Issue 1, pp. 129-137, (2017) (PubMed).

de Jesus, Spadacci-Morena, dos Anjos Rabelo, Pinfildi, Fukuda, Plapler: "Low-level laser therapy in IL-1β, COX-2, and PGE2 modulation in partially injured Achilles tendon." in: Lasers in medical science, Vol. 30, Issue 1, pp. 153-8, (2015) (PubMed).

Target Details for PTGES2

Target: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Alternative Name: PGES2

Background:

Synonyms: Gbf1, Pges2, C79137, Mpges2, 6138H1Rik, Prostaglandin E synthase 2, GATE-binding factor 1, GBF-1, Microsomal prostaglandin E synthase 2, mPGES-2, Ptges2,

Background: Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (By similarity). May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB, however, the relevance of transcription activation activity remains unclear.

Gene ID: 96979

UniProt: Q8BWM0

Pathways: Interferon-gamma Pathway, Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome