CNTNAP2 antibody (AA 363-1159) (Fluoro647)

Catalog No. ABIN7981655

The Fluoro647-conjugated Rabbit Polyclonal anti-CNTNAP2 antibody (ABIN7981655) specifically detects CNTNAP2 in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for CNTNAP2 antibody (AA 363-1159) (Fluoro647) (ABIN7981655)

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNTNAP2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-CNTNAP2 Antibody (Fluoro647)

Binding Specificity: AA 363-1159

Purpose: Anti-Caspr2/CNTNAP2 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Caspr2/CNTNAP2 recombinant protein (Position: N363-E1159).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CNTNAP2

Target: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Alternative Name: CNTNAP2

Background:

Background: Contactin-associated protein-like 2 is a protein that in humans is encoded by the CNTNAP2 gene. This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5 % of chromosome 7 and is one of the largest genes in the human genome. It is ly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability.

Gene Full Name: contactin associated protein 2

Gene ID: 26047

UniProt: Q9UHC6