CLASP2 antibody (AA 266-1230) (PE)

Catalog No. ABIN7983571

The Rabbit Polyclonal anti-CLASP2 antibody is suitable to detect CLASP2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for CLASP2 antibody (AA 266-1230) (PE) (ABIN7983571)

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLASP2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CLASP2 Antibody (PE)

Binding Specificity: AA 266-1230

Purpose: Anti-CLASP2 Antibody PE Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CLASP2 recombinant protein (Position: A266-D1230).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CLASP2

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Alternative Name: CLASP2

Background:

Background: CLASP2 (CLIP-associating protein 2) is a brain specific protein belongs to CLASP family. CLASP1 and CLASP2 regulate microtubule plus-end dynamics in brine cortex. CLASP2 is required for the orientation of stabilized microtubules toward the leading edge, It may act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms. Phosphorylation of CLASP2 by GSK3B may negatively regulate binding to microtubule lattices in lamella.

Gene Full Name: cytoplasmic linker associated protein 2

Gene ID: 23122

UniProt: O75122

Pathways: Microtubule Dynamics, Maintenance of Protein Location