DLEC1 antibody (AA 124-1622) (Biotin)

Catalog No. ABIN7984764

This Rabbit Polyclonal antibody specifically detects DLEC1 in ELISA, WB and IHC. It exhibits reactivity toward Mouse and Rat.

Quick Overview for DLEC1 antibody (AA 124-1622) (Biotin) (ABIN7984764)

Target: DLEC1 (Deleted in Lung and Esophageal Cancer 1 (DLEC1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLEC1 antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DLEC1 Antibody (Biotin)

Binding Specificity: AA 124-1622

Purpose: Anti-DLEC1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DLEC1 recombinant protein (Position: E124-Q1622).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DLEC1

Target: DLEC1 (Deleted in Lung and Esophageal Cancer 1 (DLEC1))

Alternative Name: DLEC1

Background:

Background: The cytogenetic location of this gene is 3p21.3, and it is located in a region that is commonly deleted in a variety of malignancies. Down-regulation of this gene has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of this gene in tumor cells is a result of aberrant promoter methylation. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins.

Gene Full Name: DLEC1 cilia and flagella associated protein

Gene ID: 9940

UniProt: Q9Y238