Deoxyguanosine Kinase antibody (AA 76-277)

Catalog No. ABIN7984853

The Rabbit Polyclonal anti-Deoxyguanosine Kinase antibody (ABIN7984853) specifically detects Deoxyguanosine Kinase in ELISA, WB and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for Deoxyguanosine Kinase antibody (AA 76-277) (ABIN7984853)

Target: Deoxyguanosine Kinase (DGUOK)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Deoxyguanosine Kinase antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Deoxyguanosine Kinase Antibody

Binding Specificity: AA 76-277

Purpose: Anti-DGUOK Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-DGUOK Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DGUOK recombinant protein (Position: Q76-L277).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Deoxyguanosine Kinase

Target: Deoxyguanosine Kinase (DGUOK)

Alternative Name: DGUOK

Background:

Background: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Gene Full Name: deoxyguanosine kinase

Molecular Weight: 28 kDa

Gene ID: 1716

UniProt: Q16854

Pathways: Ribonucleoside Biosynthetic Process