Deoxyguanosine Kinase antibody (AA 76-277) (APC)

Catalog No. ABIN7984861

The Rabbit Polyclonal anti-Deoxyguanosine Kinase antibody is suitable to detect Deoxyguanosine Kinase in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for Deoxyguanosine Kinase antibody (AA 76-277) (APC) (ABIN7984861)

Target: Deoxyguanosine Kinase (DGUOK)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Deoxyguanosine Kinase antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Deoxyguanosine Kinase Antibody (APC)

Binding Specificity: AA 76-277

Purpose: Anti-DGUOK Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DGUOK recombinant protein (Position: Q76-L277).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Deoxyguanosine Kinase

Target: Deoxyguanosine Kinase (DGUOK)

Alternative Name: DGUOK

Background:

Background: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Gene Full Name: deoxyguanosine kinase

Gene ID: 1716

UniProt: Q16854

Pathways: Ribonucleoside Biosynthetic Process