Desmin antibody (AA 1-304) (HRP)

Catalog No. ABIN7984937

The HRP-conjugated Rabbit Polyclonal anti-Desmin antibody (ABIN7984937) specifically detects Desmin in WB, IHC and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Desmin antibody (AA 1-304) (HRP) (ABIN7984937)

Target: Desmin (DES)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmin antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Desmin Antibody (HRP)

Binding Specificity: AA 1-304

Purpose: Anti-Desmin Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Desmin shares 97% amino acid (aa) sequence identity with both mouse,rat Desmin.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Desmin recombinant protein (Position: M1-T304). Human Desmin shares 97% amino acid (aa) sequence identity with both mouse and rat Desmin.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Desmin

Target: Desmin (DES)

Alternative Name: DES

Background:

Background: DES, also called desmin, is a protein that in humans is encoded by the DES gene, and this gene is mapped to 2q35. DES is the muscle-specific member of the intermediate filament (IF) protein family. It is one of the earliest myogenic markers, both in heart and somites, and is expressed in satellite stem cells and replicating myoblasts. DES is very important in muscle cell architecture and structure since it connects many components of the cytoplasm. It may be also play an important role in mitochondria function. What's more, DES provides attachments between the terminal Z disc and membrane-associated proteins to form a force-transmitting system that parallels the thin filaments at myotendinous junctions.

Gene Full Name: desmin

Sequence Similarities: Belongs to the intermediate filament family.

Gene ID: 1674

UniProt: P17661