ERCC3 antibody (AA 68-377) (Cy3)

Catalog No. ABIN7985941

The Rabbit Polyclonal anti-ERCC3 antibody is suitable to detect ERCC3 in samples from Human. It has been validated for FACS.

Quick Overview for ERCC3 antibody (AA 68-377) (Cy3) (ABIN7985941)

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC3 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-ERCC3 Antibody (Cy3)

Binding Specificity: AA 68-377

Purpose: Anti-XPB/ERCC3 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human XPB/ERCC3 recombinant protein (Position: K68-Q377).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ERCC3

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Alternative Name: ERCC3

Background:

Background: XPB (xeroderma pigmentosum type B) is an ATP-dependent DNA helicase in humans that is a part of the TFIIH transcription factor complex. This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

Gene Full Name: ERCC excision repair 3, TFIIH core complex helicase subunit

Gene ID: 2071

UniProt: P19447

Pathways: DNA Damage Repair