DPH5 antibody (AA 11-250) (Fluoro488)

Catalog No. ABIN7986344

The Fluoro488-conjugated Rabbit Polyclonal anti-DPH5 antibody (ABIN7986344) specifically detects DPH5 in FACS. The antibody is reactive with Human samples.

Quick Overview for DPH5 antibody (AA 11-250) (Fluoro488) (ABIN7986344)

Target: DPH5 (DPH5 Homolog (DPH5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPH5 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-DPH5 Antibody (Fluoro488)

Binding Specificity: AA 11-250

Purpose: Anti-DPH5 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DPH5 recombinant protein (Position: D11-H250).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DPH5

Target: DPH5 (DPH5 Homolog (DPH5))

Alternative Name: DPH5

Background:

Background: Diphthine synthase is an enzyme that in humans is encoded by the DPH5 gene. This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: diphthamide biosynthesis 5

Gene ID: 51611

UniProt: Q9H2P9

Pathways: SARS-CoV-2 Protein Interactome