DPY19L1 antibody (AA 354-657) (APC)

Catalog No. ABIN7986360

This Rabbit Polyclonal antibody specifically detects DPY19L1 in FACS. It exhibits reactivity toward Human.

Quick Overview for DPY19L1 antibody (AA 354-657) (APC) (ABIN7986360)

Target: DPY19L1 (Dpy-19-Like 1 (C. Elegans) (DPY19L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPY19L1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-DPY19L1 Antibody (APC)

Binding Specificity: AA 354-657

Purpose: Anti-DPY19L1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DPY19L1 recombinant protein (Position: L354-H657).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DPY19L1

Target: DPY19L1 (Dpy-19-Like 1 (C. Elegans) (DPY19L1))

Alternative Name: DPY19L1

Background:

Background: Dpy-19 (dumpy-19), is a 683 amino acid C. elegans protein that is required to orient the neuroblasts QL and QR correctly on the anterior/posterior axis. Dpy-19 is expressed highly in dorsal hyp7 cells, ventral P cells and lateral V cells, and dorsal and ventral body muscle cells. DPY19L1 (Dpy-19-like protein 1), also known as KIAA0877, is a 675 amino acid multi-pass membrane protein that belongs to the Dpy-19 family. DPY19L1 is expressed as two isoforms produced by alternative splicing and is encoded by a gene mapping to human chromosome 7, which encodes over 1,000 genes and makes up about 5 % of the human genome. Diseases associated with chromosome 7 include Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Gene Full Name: dpy-19 like C-mannosyltransferase 1

Gene ID: 23333

UniProt: Q2PZI1

Pathways: SARS-CoV-2 Protein Interactome