DBN1 antibody (AA 9-649) (Cy3)

Catalog No. ABIN7986388

The Mouse Monoclonal anti-DBN1 antibody is suitable to detect DBN1 in samples from Human, Rat, Mouse and Monkey. It has been validated for FACS.

Quick Overview for DBN1 antibody (AA 9-649) (Cy3) (ABIN7986388)

Target: DBN1 (Drebrin 1 (DBN1))

Reactivity: Human, Rat, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This DBN1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Clone: 4F6E7

Product Details anti-DBN1 Antibody (Cy3)

Binding Specificity: AA 9-649

Purpose: Anti-Drebrin/DBN1 Antibody (monoclonal, 4F6E7) Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Drebrin/DBN1 recombinant protein (Position: H9-D649).

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DBN1

Target: DBN1 (Drebrin 1 (DBN1))

Alternative Name: DBN1

Background:

Background: Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.

Gene Full Name: drebrin 1

Gene ID: 1627

UniProt: Q16643

Pathways: Maintenance of Protein Location