DBN1 antibody (AA 9-649) (HRP)

Catalog No. ABIN7986393

This Mouse Monoclonal antibody specifically detects DBN1 in WB, IHC and ELISA. It exhibits reactivity toward Human, Rat, Mouse and Monkey.

Quick Overview for DBN1 antibody (AA 9-649) (HRP) (ABIN7986393)

Target: DBN1 (Drebrin 1 (DBN1))

Reactivity: Human, Rat, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This DBN1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4F6E7

Product Details anti-DBN1 Antibody (HRP)

Binding Specificity: AA 9-649

Purpose: Anti-Drebrin/DBN1 Antibody (monoclonal, 4F6E7) HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Drebrin/DBN1 recombinant protein (Position: H9-D649).

Isotype: IgG2a

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DBN1

Target: DBN1 (Drebrin 1 (DBN1))

Alternative Name: DBN1

Background:

Background: Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.

Gene Full Name: drebrin 1

Gene ID: 1627

UniProt: Q16643

Pathways: Maintenance of Protein Location