DNM2 antibody (AA 498-785) (Fluoro647)

Catalog No. ABIN7986598

The Rabbit Polyclonal anti-DNM2 antibody is suitable to detect DNM2 in samples from Human. It has been validated for FACS.

Quick Overview for DNM2 antibody (AA 498-785) (Fluoro647) (ABIN7986598)

Target: DNM2 (Dynamin 2 (DNM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNM2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-DNM2 Antibody (Fluoro647)

Binding Specificity: AA 498-785

Purpose: Anti-Dynamin 2/DNM2 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Dynamin 2/DNM2 recombinant protein (Position: N498-R785).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DNM2

Target: DNM2 (Dynamin 2 (DNM2))

Alternative Name: DNM2

Background:

Background: Dynamin-2 is a protein that in humans is encoded by the DNM2 gene. Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

Gene Full Name: dynamin 2

Gene ID: 1785

UniProt: P50570

Pathways: Toll-Like Receptors Cascades