EML4 antibody (AA 207-423) (Biotin)

Catalog No. ABIN7987100

The Biotin-conjugated Rabbit Polyclonal anti-EML4 antibody (ABIN7987100) specifically detects EML4 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for EML4 antibody (AA 207-423) (Biotin) (ABIN7987100)

Target: EML4 (Echinoderm Microtubule Associated Protein Like 4 (EML4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EML4 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-EML4 Antibody (Biotin)

Binding Specificity: AA 207-423

Purpose: Anti-EML4 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human EML4 recombinant protein (Position: K207-N423).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EML4

Target: EML4 (Echinoderm Microtubule Associated Protein Like 4 (EML4))

Alternative Name: EML4

Background:

Background: Echinoderm microtubule-associated protein-like 4 is a protein that in humans is encoded by the EML4gene. This gene is a member of the echinoderm microtubule associated protein-like family, and it mapped to 2p21. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.

Gene Full Name: EMAP like 4

Gene ID: 27436

UniProt: Q9HC35