EHD2 antibody (Middle Region) (Fluoro550)

Catalog No. ABIN7987259

The Fluoro550-conjugated Rabbit Polyclonal anti-EHD2 antibody (ABIN7987259) specifically detects EHD2 in FACS. The antibody is reactive with Human samples.

Quick Overview for EHD2 antibody (Middle Region) (Fluoro550) (ABIN7987259)

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHD2 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-EHD2 Antibody (Fluoro550)

Binding Specificity: Middle Region

Purpose: Anti-EHD2 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human EHD2, which shares 100% and 95% amino acid (aa) sequence identity with mouse and rat EHD2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for EHD2

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Alternative Name: EHD2

Background:

Background: EH-domain containing 2, also known as EHD2, is a human gene[5] belonging to the EHD protein family. This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.

Gene Full Name: EH domain containing 2

Gene ID: 30846

UniProt: Q9NZN4

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development