EHD2 antibody (Middle Region)

Catalog No. ABIN7987266

This Rabbit Polyclonal antibody specifically detects EHD2 in WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for EHD2 antibody (Middle Region) (ABIN7987266)

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EHD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-EHD2 Antibody

Binding Specificity: Middle Region

Purpose: Anti-EHD2 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-EHD2 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human EHD2, which shares 100% and 95% amino acid (aa) sequence identity with mouse and rat EHD2, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EHD2

Target: EHD2 (EH-Domain Containing 2 (EHD2))

Alternative Name: EHD2

Background:

Background: EH-domain containing 2, also known as EHD2, is a human gene[5] belonging to the EHD protein family. This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.

Gene Full Name: EH domain containing 2

Molecular Weight: 61 kDa

Gene ID: 30846

UniProt: Q9NZN4

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development