ENDOU antibody (AA 20-386) (Fluoro550)

Catalog No. ABIN7987556

The Fluoro550-conjugated Rabbit Polyclonal anti-ENDOU antibody (ABIN7987556) specifically detects ENDOU in FACS. The antibody is reactive with Human samples.

Quick Overview for ENDOU antibody (AA 20-386) (Fluoro550) (ABIN7987556)

Target: ENDOU (Endonuclease, PolyU-Specific (ENDOU))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENDOU antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-ENDOU Antibody (Fluoro550)

Binding Specificity: AA 20-386

Purpose: Anti-PP11/ENDOU Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PP11/ENDOU recombinant protein (Position: K20-T386).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ENDOU

Target: ENDOU (Endonuclease, PolyU-Specific (ENDOU))

Alternative Name: ENDOU

Background:

Background: Endonuclease, poly(U) specific is a protein that in humans is encoded by the ENDOU gene. This gene encodes a protein with endoribonuclease activity that binds polyuridine-enriched single-stranded RNA. This gene was initially characterized based on its high expression in placenta but was mischaracterized as a serine protease. In mouse, this gene promotes tolerance to self-antigens by regulating B cell activation-induced cell death (AICD). The protein may be useful as a tumor marker. Multiple alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Gene Full Name: endonuclease, poly(U) specific

Gene ID: 8909

UniProt: P21128