ERN2 antibody (AA 517-919) (APC)

Catalog No. ABIN7987660

The Rabbit Polyclonal anti-ERN2 antibody is suitable to detect ERN2 in samples from Human. It has been validated for FACS.

Quick Overview for ERN2 antibody (AA 517-919) (APC) (ABIN7987660)

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERN2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-ERN2 Antibody (APC)

Binding Specificity: AA 517-919

Purpose: Anti-ERN2 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ERN2 recombinant protein (Position: K517-P919).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ERN2

Target: ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))

Alternative Name: ERN2

Background:

Background: ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.

Gene Full Name: endoplasmic reticulum to nucleus signaling 2

Gene ID: 10595

UniProt: Q76MJ5