Epiregulin antibody (AA 24-169) (Fluoro647)

Catalog No. ABIN7988202

This Rabbit Polyclonal antibody specifically detects Epiregulin in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Epiregulin antibody (AA 24-169) (Fluoro647) (ABIN7988202)

Target: Epiregulin (EREG)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epiregulin antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-Epiregulin Antibody (Fluoro647)

Binding Specificity: AA 24-169

Purpose: Anti-EREG Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human EREGshares 84.1%,83.4% amino acid (aa) sequence identity with mouse,rat EREG,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human EREG recombinant protein (Position: F24-V169). Human EREGshares 84.1% and 83.4% amino acid (aa) sequence identity with mouse and rat EREG, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Epiregulin

Target: Epiregulin (EREG)

Alternative Name: EREG

Background:

Background: This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues.

Gene Full Name: epiregulin

Gene ID: 2069

UniProt: O14944

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation